As this Bloomberg map shows, Malaysian flight 370 is not the first flight to mysteriously disappear. 83 flights have vanished since 1948; 80 of them never to be found again (the dots in yellow). This map only includes flights capable of carrying more than 14 passengers.
Some more curious stats:
--Five planes were missing in the Bermuda Triangle
--The DC-3 is the airplane with the higher count of disappearances: 19
--The average number of people missing: 13
--The average number of vanished flight per year: 1.2
Check out the full Bloomberg infographic here.